Introduction to Statistical Methods for Clinical Trials by Thomas D Cook (9781584880271)
Introduction to Statistical Methods for Clinical Trials by Thomas D Cook (9781584880271)
Introduction to Statistical Methods for Clinical Trials (Book)
Thomas D Cook Release Date: January 2008 Format: Hardback Pages: 464 ISBN: 9781584880271 ISBN-10: 1584880279
Clinical trials have taken a prominent role in the research and approval of new drugs. To conduct rigorous clinical studies, present and future biostatisticians need a good background in the design and analysis of data gleaned from those studies. This text provides a summary of statistical design, including cross-over designs, sample size estimation, sequential methods for interim analyses, survival analysis, and repeated measures. The authors also discuss a number of topics not addressed in other books on the subject, including the use of surrogate variables, meta-analysis, and longitudinal designs. Each chapter includes examples and exercises, and data sets are available for download from the Internet.
